کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7585300 1492034 2018 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glycosaminoglycanomic profiling of human milk in different stages of lactation by liquid chromatography-tandem mass spectrometry
ترجمه فارسی عنوان
پروفیل گلیکواسامینوگلیکانومیک شیر در مراحل مختلف شیردهی با استفاده از اسپکترومتری جرمی کروماتوگرافی-دو طرفه
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Glycans in human milk serve several important biological functions that promote infant health. As kind of important glycans, glycosaminoglycans (GAGs) are a complex family of polyanionic carbohydrate, participating in a variety of critical physiological and pathological processes. In this study, the content and the detailed composition of human milk GAGs from Chinese mothers in different stages of lactation, based on a liquid chromatography-tandem mass spectrometry approach was investigated. The results showed that the GAG fraction in the human milk samples was very complex as it was composed of heparan sulfate, chondroitin sulfate, and hyaluronic acid. With lactation extending, the total amount of GAGs in human milk decreased. This study provided an important guide for the demands of GAGs during different stages of lactation. The results were also beneficial for studies on the composition and functional properties of infant formula.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 258, 30 August 2018, Pages 231-236
نویسندگان
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