کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7586423 1492047 2018 25 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hydroxycinnamic acids loaded in lipid-core nanocapsules
ترجمه فارسی عنوان
اسیدهای هیدروکسی کینیک که در نانوکپسولهای چربی هسته قرار می گیرند
کلمات کلیدی
نانوکپسولهای لیپید هسته، پلی (Î-کاپرولاکتون)، پلی فنول های بیولوژیکی، اسیدهای هیدروکسین کیمیا، بع بع،
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Ferulic, caffeic, sinapic, and coumaric acids, belonging to the class of hydroxycinnamic acids (HAs), are bioactive polyphenols widespread in the plant kingdom and present in the human diet. Due to their biological properties and effects in the prevention of various diseases associated with oxidative stress, HAs can be exploited for attractive nutraceutical applications. Starting from this and in order to increase bioaccessibility, we encapsulated HAs in lipid-core nanocapsules (NCs) based on a biodegradable and biocompatible poly(ε-caprolactone) polymer. The results showed that nanoparticles loaded with hydroxycinnamic acids (HA-NCs) have diameter of 224-253 nm, encapsulation efficiency of 53-78%, and are stable over time (30 days). In vitro tests evidenced that NCs are able to preserve HAs in the gastric simulated fluid and release them in the intestinal simulated fluid. The delivery system developed could be employed to create novel functional foods.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 245, 15 April 2018, Pages 551-556
نویسندگان
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