کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7592560 1492114 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Enhanced biological activity of carotenoids stabilized by phenyl groups
ترجمه فارسی عنوان
فعالیت زیستی پیشرفته کاروتنوئید ها توسط گروه های فنلی تثبیت شده است
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Carotenoids are lipid soluble food ingredients with multifunction including antioxidant and anticancer activities. However, carotenoids are destructively oxidized upon reaction with radicals resulting in toxic effects on biological systems. Two synthetic carotenoids (BAS and BTS) containing the aromatic phenyl groups with a para-substituent (OMe and Me, respectively) at C-13 and C-13′ position were prepared in order to overcome a structural instability of carotenoid. Both BAS and BTS exerted stronger radical scavenging activity than β-carotene in DPPH and ABTS assays. In particular, BTS significantly reduced in vivo ROS (reactive oxygen species) levels and improved body growth and reproduction of Caenorhabditiselegans. BTS has a great potential for the advanced and modified carotenoid material with stability leading to enhanced bioavailability.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 177, 15 June 2015, Pages 339-345
نویسندگان
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