کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7594802 | 1492122 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Plasma cholesterol-raising potency of dietary free cholesterol versus cholesteryl ester and effect of β-sitosterol
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
The present study (i) compared plasma cholesterol-raising activity of free cholesterol (FC) with that of cholesteryl palmitate (CP) and (ii) examined plasma cholesterol-reducing activity of β-sitosterol in FC-induced and CP-induced hypercholesterolemia. Male hamsters were divided into five groups and fed one of the five diets containing no cholesterol (NC), 2.6 mmol cholesterol (C), 2.6 mmol cholesterol plus 2.6 mmol β-sitosterol (C+S), 2.6 mmol cholesteryl palmitate (CP), and 2.6 mmol CP plus 2.6 mmol β-sitosterol (CP+S), respectively, for 8 weeks. Hamsters fed diet C had plasma TC of 317.5 mg/dl whereas hamsters fed diet CP has plasma TC of 281.3 mg/dl. β-Sitosterol reduced plasma TC by 17.4% and 11.6%, respectively, in FC-induced and CP-induced hypercholesterolemia (not significant). It was concluded that plasma cholesterol-raising activity of dietary cholesterol was a function of its chemical forms in diet, and β-sitosterol could similarly suppress the hypercholesterolemia induced by both dietary FC and CP.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 169, 15 February 2015, Pages 277-282
Journal: Food Chemistry - Volume 169, 15 February 2015, Pages 277-282
نویسندگان
Yuwei Liu, Lin Lei, Xiaobo Wang, Ka Ying Ma, Yuk Man Li, Lijun Wang, Sun Wa Man, Yu Huang, Zhen-Yu Chen,