Inhibition of biofilm development of uropathogens by curcumin - An anti-quorum sensing agent from Curcuma longa

- Sub-MIC concentrations of curcumin effectively inhibit quorum sensing and in vitro biofilm formation in uropathogens.
- Sub-MIC concentrations of curcumin also disintegrate mature biofilms of uropathogens.
- Curcumin acts synergistically with conventional antibiotics and enhanced bacterial susceptibility towards antibiotics.