An LC-MS/MS method for determination of jujuboside A in rat plasma and its application to pharmacokinetic studies

► It firstly developed a LC-MS/MS method for measurement of jujuboside A in rat plasma. ► It firstly reported the pharmacokinetic profile of jujuboside A in rats. ► The lower limit of quantification (LLOQ) of developed LC-MS/MS method was lower than the previous report.