کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7624910 | 1494554 | 2014 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Structural identification of compounds from Toona sinensis leaves with antioxidant and anticancer activities
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The aim of this study was to isolate key active compounds from Toona sinensis leaves (TSL) with antioxidant and anticancer activities. Four compounds, quercetin-3-O-α-L-rhamnopyranoside (QLR), kaempferol-3-O-α-L-rhamnopyranoside (KLR), 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose (PGG) and ethyl gallate (EG), were purified from the ethyl acetate fraction of TSL by column chromatography. Their structures were identified by mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectrometry analyses. All four compounds exhibited strong antioxidant activities (including ABTS radical scavenging activities and ORAC values). PGG showed the strongest antioxidant activity. KLR showed the strongest anticancer activities against human hepatoma HepG2 and human breast cancer MCF-7 cells. QLR, PGG, and EG showed relatively weak anticancer activities. These results suggest that four compounds are key chemical compositions valuable for preparing functional foods in the food industry.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 10, September 2014, Pages 427-435
Journal: Journal of Functional Foods - Volume 10, September 2014, Pages 427-435
نویسندگان
Wei Zhang, Chao Li, Li-Jun You, Xiong Fu, Yong-Sheng Chen, Yu-Qin Luo,