Elucidation of the dynamic nature of interactome networks: A practical tutorial

This tutorial presents a simplified pipeline for the analysis of the network of interactions of a protein in order to reach to a biological interpretation of the mechanisms modulated by those interactions, which constitutes an important way to understand proteins' functions and the molecular mechanisms in which those proteins are involved. Moreover, when interactomics is applied to perform an in-depth molecular analysis of novel disease proteins, it can result in an understanding of disease-causing mechanisms and create drug discovery opportunities. Nevertheless, the pipeline presented can be also useful for the analysis of dynamic alterations of other biomolecules.