Proteome of the porosome complex in human airway epithelia: Interaction with the cystic fibrosis transmembrane conductance regulator (CFTR)

Schematic drawing showing interactions between the cystic fibrosis transmembrane conductance regulator (CFTR) and the porosome complex at the cell plasma membrane in human airway epithelia. The possible regulation by CFTR on the quality of mucus secreted via the porosome complex, such as highly viscous mucus resulting from CFTR defects is hypothesized.120