Light scattering on the structural characterization of DMPG vesicles along the bilayer anomalous phase transition

► Consistent results on radii from SLS and DLS for “normal” DMPC and DMPG vesicles. ► In DMPG transition region, different from DSL, SLS indicates a huge vesicle growth. ► Though swollen in the gel-fluid transition region, DMPG vesicles are isotropic. ► Bilayer pores with superfluid rims explain huge radius increase. ► Non-Stokes viscous force on porous vesicles explains DLS/SLS discrepancy.