Metallopeptide catalysts and artificial metalloenzymes containing unnatural amino acids

- Metal-peptide hybrids have unique potential for catalysis.
- Unnatural amino acids (UAAs) can be used to create novel hybrid catalysts.
- Several methods have been developed to incorporate UAAs into peptide scaffolds.
- Promising levels of selectivity have been demonstrated for several hybrid catalysts.
- Methods to design and optimize hybrid catalysts are needed for practical applications.