Transition-metal-mediated uncaging in living human cells - an emerging alternative to photolabile protecting groups

- Bioorthogonal activation of caged substrates by transition metal compounds.
- Organopalladium-mediated modulation of protein activity within cells.
- Palladium-nanoparticle-mediated activation of toxigenic prodrugs in the extracellular space.
- Organoruthenium-mediated activation of a toxigenic prodrug within cells.
- Organoiron-mediated activation of a fluorogenic compound within cells.