Oxygen-evolving complex of Photosystem II: an analysis of second-shell residues and hydrogen-bonding networks

- An extensive and interconnected hydrogen-bonding network surrounds the OEC in PSII.
- This network stabilizes intermediates of the OEC during water oxidation.
- Three distinct channels have been identified that transport water, protons, and O2.
- Changing second-shell residues of the OEC affects the efficiency of water oxidation.