New developments in 'ene'-reductase catalysed biological hydrogenations

- Old Yellow Enzymes are primarily used for biocatalytic hydrogenations.
- Medium chain dehydrogenase/reductases can substitute for OYEs.
- Unsaturated ester reduction can occur with extra electron withdrawing substituents.
- Chemoenzymatic or biocatalytic multienzyme cascading reactions are possible.
- Optimisation of biocatalytic processes can improve commercial viability.