کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7753662 1499402 2018 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel polypyridyl ruthenium complexes acting as high affinity DNA intercalators, potent transcription inhibitors and antitumor reagents
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Novel polypyridyl ruthenium complexes acting as high affinity DNA intercalators, potent transcription inhibitors and antitumor reagents
چکیده انگلیسی
Six novel polypyridyl Ru(II) complexes have been found to bind DNA very tightly through intercalation and serve as high efficient DNA transcription and topoisomerase inhibitors. They have moderate cytotoxicity towards four tumor cell lines but very low cytotoxicity to normal cell, suggesting good potential as antitumor drugs.92
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Inorganic Biochemistry - Volume 185, August 2018, Pages 1-9
نویسندگان
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