Cross-linked cytochrome P450 BM3 aggregates promoted by Ru(II)-diimine complexes bearing aldehyde groups

Several Ru(II)-diimine complexes bearing aldehyde moieties are suitable cross-linkers for the immobilization of cytochrome P450 BM3 variants. The heterogeneous biocatalyst peroxygenase activity often matches, and after several rounds of reactions, exceeds that of its homogeneous counterpart.305