Cationic Au(I) complexes with aryl-benzothiazoles and their antibacterial activity

Au(I) complexes of the type [(PPh3)Au(arylbenzothiazole)]OTf (OTf = trifluoromethanesulfonate) exhibit strong antibacterial effects through binding of the reactive [(PPh3)Au]+ fragment to S-containing biomolecules in the cytosol.87