A study of the properties, reactivity and anticancer activity of novel N-methylated-3-thiazolyl or 3-thienyl carbazoles and their Pd(II) and Pt(II) complexes

Two new N-methylated carbazoles and the Pd(II) and Pt(II) complexes are reported together with a comparative study of their properties, cytotoxic activities (on HCT116, MCF7 and MDA-MB231 cancer cell lines) and their abilities to act as DNA intercalators or inhibitors of cathepsin and Topoisomerases (I or IIα).213