Bioactive ruthenium(II)-arene complexes containing modified 18β-glycyrrhetinic acid ligands

Two novel Ru-arene complexes with modified 18β-glycyrrhetinic acid ligand, which is an active species of natural medicine, exhibited significant anti-proliferative and anti-microbial activity. Further studies indicate that the two complexes can induce condensation of DNA and enhancement of intracellular ROS levels.190