Sulfonated Schiff base Sn(IV) complexes as potential anticancer agents

Synthesis and crystal structure of a sulfonated Schiff base 2-[(2,3-dihydroxyphenyl)methylideneamino]benzenesulfonic acid trihydrate and its diphenoxo-bridged diorganotin(IV) derivatives 1 and 2 are described. Antiproliferative efficacies of 1 and 2 are evaluated on cancer cell lines and IC50 values prove a substantial cytotoxicity of 2 towards A-549 lung cancer cell line.240