The adipogenic potential of Cr(III). A molecular approach exemplifying metal-induced enhancement of insulin mimesis in diabetes mellitus II

Confronting the challenge of insulin mimesis in Diabetes mellitus II prompted perusal of Cr(III)-citrate adipogenetic potential in 3T3-L1 cells. Well-defined Cr(III) species rises atoxic and starkly efficient toward adipocyte differentiation-maturation. Migration studies attest to atoxicity, with key molecular targets involved in unique Cr(III)-linked insulin-enhancement of adipocyte activity reducing hyperglycemia.98