Synthesis, characterization, and evaluation of the antimicrobial potential of copper(II) coordination complexes with quinolone and p-xylenyl-linked quinolone ligands

The antimicrobial efficacy of copper(II) has been known to mankind since the ancient times. In an attempt to combine the antimicrobial effect of copper(II) with known antimicrobial agents, Cu2 + coordination complexes of quinolones and p-xylenyl-linked quinolone dimers were synthesized, characterized, and their efficacy against nosocomial pathogens evaluated.104