Cationic Pd(II)/Pt(II) 5,5-diethylbarbiturate complexes with bis(2-pyridylmethyl)amine and terpyridine: Synthesis, structures,DNA/BSA interactions, intracellular distribution, cytotoxic activity and induction of apoptosis

New Pd(II)/Pt(II) 5,5-diethylbarbiturate complexes with bis(2-pyridylmetyl)amine and terpyridine display high binding affinity towards DNA/BSA as explored by various physical and biochemical methods. In addition, the Pd(II) complexes show selectivity against HT-29 (colon) and MCF-7 (breast) cell lines.