In vitro antitumor activity of free and nano-encapsulated Na5[PMo10V2O40]·nH2O and its binding properties with ctDNA by using combined spectroscopic methods

The free and nano-encapsulated forms of PMoV in starch and lipid nanocarriers showed a remarkable inhibitory effect on two types of cancer cells. The interaction mechanism of PMoV to ctDNA ruled out the presence of any direct coordinate covalent bond formation and proposed the groove or outside stacking binding mode.