The second generation of iodido complexes: trans-[PtI2(amine)(amine′)] bearing different aliphatic amines

The antitumoral potential for platinum iodido complexes bearing different aliphatic amines was studied. One of the complexes is especially active towards cell lines where cisplatin has no effect. These complexes' interaction with biological models such as pBR322, 5′-GMP, 9EtG, N-AcMet and N-AcCys has been studied and compared to cisplatin's