Relevance of copper transporter 1 for cisplatin resistance in human ovarian carcinoma cells

► No influence of copper on cisplatin accumulation and on cisplatin cytotoxicity. ► CTR1 is localised in the perinuclear region (partly in trans-Golgi network). ► Continuous recycling of CTR1 between the perinuclear region and cell surface. ► CTR1 co-localisation with a fluorescent cisplatin analogue (endocytosis inhibited).