Copper(II) complexes with antimicrobial drug flumequine: Structure and biological evaluation

► Copper(II) complexes with first-generation quinolone flumequine. ► Three crystal structures of copper mixed-ligand flumequine complexes. ► The complexes can bind to human or bovine serum albumin protein. ► Intercalation is the most possible binding mode of the complexes to DNA.. ► The complexes can displace EB from EB-DNA complex..