Highly cytotoxic trithiolato-bridged dinuclear Rh(III) and Ir(III) complexes

Water-soluble trithiolato-bridged pentamethylcyclopentadienyl Rh(III) and Ir(III) complexes have been synthesized and characterized. The cytotoxicity of all complexes has been established using cancerous and noncancerous cell lines. The cationic complexes are highly cytotoxic, with IC50 values in the nanomolar range.