Bacterial cell division proteins as antibiotic targets

- PBP1B crystal structure access inhibition of its GTase activity.
- Inhibition of FtsZ polymerization cures mice from Staphylococcusaureus infection.
- FtsW and MraY activity assays and structures enable development of inhibitors.
- FtsQLB surface interaction studies enable search for inhibitors of this interaction.
- In cell screening assays based on specific targets are needed.