Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents

Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 24, Issue 21, 1 November 2016, Pages 5162-5171

Irene Sola, Albert Artigas, Martin C. Taylor, F. Javier Pérez-Areales, Elisabet Viayna, M. Victòria Clos, Belén Pérez, Colin W. Wright, John M. Kelly, Diego Muñoz-Torrero,