Harnessing biosynthesis and quantitative NMR for late stage functionalization of lead molecules: Application to the M1 positive allosteric modulator (PAM) program

Harnessing biosynthesis and quantitative NMR for late stage functionalization of lead molecules: Application to the M1 positive allosteric modulator (PAM) program

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 11, 15 June 2018, Pages 2068-2073

Michael A. Brodney, Raman Sharma, John T. Lazzaro, Gregory S. Walker, R. Scott Obach,