Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors

Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 10, 1 June 2018, Pages 1811-1816

Michael J. Bennett, Yiqin Wu, Amogh Boloor, Jennifer Matuszkiewicz, Shawn M. O'Connell, Lihong Shi, Ryan K. Stansfield, Joselyn R. Del Rosario, James M. Veal, David J. Hosfield, Jiangchun Xu, Stephen W. Kaldor, Jeffrey A. Stafford, Juan M. Betancort,