Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors

Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 9, 15 May 2018, Pages 1615-1620

Xiao Ding, Luigi Piero Stasi, Ming-Hsun Ho, Baowei Zhao, Hailong Wang, Kai Long, Qiongfeng Xu, Yingxia Sang, Changhui Sun, Huan Hu, Haihua Yu, Zehong Wan, Lizhen Wang, Colin Edge, Qian Liu, Yi Li, Kelly Dong, Xiaoming Guan, Feng Ren,