کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7784003 | 1500574 | 2018 | 41 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, thermal properties and cell-compatibility of photocrosslinked cinnamoyl-modified hydroxypropyl cellulose
ترجمه فارسی عنوان
سنتز، خواص حرارتی و سازگاری سلول هیدروکسی پروپیل سلولز اصلاح شده با فینوکسلی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
چکیده انگلیسی
Biocompatibility of cinnamoyl-modified carbohydrate materials is not well-known, while they are attracting attention as a photoreactive material. In order to investigate biocompatible properties of cinnamoyl-modified carbohydrate, hydroxypropyl cellulose (HPC) was reacted with cinnamoyl chloride to yield cinnamoyl-modified HPC (HPC-C) for a cell proliferation test. HPC-Cs with three different degrees of substitution (DS) were prepared by changing a feed ratio of cinnamoyl chloride to HPC. The DS of the products ranged from 1.3 to 3.0 per one hydroxylpropyl anhydroglucose unit. Thermal analysis using DSC and TGA showed that the HPC-C with higher DS has a glass transition temperature and higher thermal stability. Ultraviolet (UV) light was irradiated on the HPC-C thin films, and changes in the UV-vis spectrum of the films were examined. In the course of UV irradiation, the absorbance at 280â¯nm was reduced. Fibroblast cells were cultured on the photocrosslinked HPC-C films, and cell growth was examined. The cell proliferation test revealed that the photocrosslinked HPC-C films have good compatibility with fibroblast cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 184, 15 March 2018, Pages 418-426
Journal: Carbohydrate Polymers - Volume 184, 15 March 2018, Pages 418-426
نویسندگان
Shinya Yano, Takumi Iwase, Naozumi Teramoto, Toshiaki Shimasaki, Mitsuhiro Shibata,