کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7785157 1500605 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antioxidant and hepatoprotective activities of polysaccharides from Anoectochilus roxburghii
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Antioxidant and hepatoprotective activities of polysaccharides from Anoectochilus roxburghii
چکیده انگلیسی
The physicochemical properties (molecular weights and monosaccharide compositions), antioxidant and hepatoprotective activities of polysaccharides (ARPPs: ARPP30, ARPP60 and ARPP80) isolated from Anoectochilus roxburghii were investigated. ARPP80 exhibited relatively strong antioxidant activities in a concentration-dependent manner. In mice subjected to carbon tetrachloride-induced hepatotoxicity, ARPP80 pretreatment significantly (p < 0.01) reduced the levels of aspartate and alanine amino transferases and malonyldialdehyde, prominently (p < 0.01) restored the levels of superoxide dismutase, catalase, glutathione peroxidase and reduced glutathione in serum or liver homogenate. These hepatoprotective effects were comparable to those of the standard drug silymarin at the same dose (200 mg/kg). The study clearly demonstrated that ARPPs, especially ARPP80, might be suitable as functional foods or hepatoprotective drugs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 153, 20 November 2016, Pages 391-398
نویسندگان
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