Liposome-loaded chitosan physical hydrogel: Toward a promising delayed-release biosystem

- Development of a biosystem entirely biocompatible and biodegradable.
- “Hybrid” system composed of phosphatidylcholine liposomes entrapped within a chitosan physical hydrogel.
- Confirmation of the presence of liposomes within the hydrogel by cryo-SEM.
- Proof of concept of delayed-release by using a model water soluble molecule (carboxyfluorescein, CF) encapsulated in liposomes, themselves incorporated into the chitosan hydrogel.