کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7793968 1500822 2016 32 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Staudinger/aza-Wittig/Grignard reaction as key step for the concise synthesis of 1-C-Alkyl-iminoalditol glycomimetics
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
The Staudinger/aza-Wittig/Grignard reaction as key step for the concise synthesis of 1-C-Alkyl-iminoalditol glycomimetics
چکیده انگلیسی

- The Staudinger/aza-Wittig Grignard reaction cascade is a concise synthetic method for the synthesis of biologically active 1-C-alkyl iminoalditol glycomimetics.
- A concise synthetic approach to biologically active 1-C-alkyl iminoalditol glycomimetics: The Staudinger/aza-Wittig Grignard reaction cascade.
- The stereoselective control of C-1 alkyl substitution can be controlled by the choice of protecting groups at the sugar substrate as well as the nature of the nucleophilic Grignard reagent in the Staudinger/aza-Wittig Grignard reaction cascade.
- Compounds exhibit selective b-glucosidase inhibition.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 429, 24 June 2016, Pages 62-70
نویسندگان
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