Influence of the configurational pattern of sp2-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties

- sp2-Iminosugar N-, S-, O- and C-octyl pseudoglycosides have been synthesized.
- Their glycosidase inhibition profiles depend on the configurational pattern.
- Several derivatives with antiproliferative activity have been identified.
- The inhibitory and antiproliferative activities are not directly related.