Evaluation of monovalent and multivalent iminosugars to modulate Candida albicans β-1,2-mannosyltransferase activities

- A library of iminosugars was screened for their effects on mannosyltransferases.
- A monovalent deoxynojirimycin derivative inhibits the transfer of mannose.
- Deoxymannojirimycin derivatives modulate the substrate specificity of CaBmt1.
- Iminosugars may be used for controlling biosynthesis of β-mannosides.