Synthesis and biological evaluation of 4-(2-(dimethylamino)ethoxy)benzohydrazide derivatives as inhibitors of Entamoeba histolyica

Hydrazones formed by the combination of two pharmacophores, the N-dimethylaminoethoxy tail and different substituted aldehydes. The hybrids (H1H30) have been evaluated against the HM1: ISS strain of E. histolytica and cell viability on lung cancer cell line (A549 cells) by MTT assay.146