One-pot microwave assisted synthesis under green chemistry conditions, antioxidant screening, and cytotoxicity assessments of benzimidazole Schiff bases and pyrimido[1,2-a]benzimidazol-3(4H)-ones

► Synthesis of benzimidazole Schiff bases and of pyrimido[1,2-a]benzimidazoles. ► Environmentally friendly conditions. ► Assignment of E-configuration to Schiff bases. ► Evaluation as inhibitors of lipoxygenase (LOX) and of lipid peroxidation (LPO). ► Promising results, e.g. good inhibition without cytotoxicity.