Trijugin- and mexicanolide-type limonoids from the fruits of Heynea trijuga that reverse multidrug resistance in MCF-7/DOX cells

The phytochemical investigation of Heynea trijuga extract yield 13 limonoids. Three of these, trijugin H and trichiconnarones A and B were effective in reversing resistance in MCF-7/DOX cells in vitro.265