Dihydro-β-agarofurans from the roots of the Australian endemic rainforest tree Maytenus bilocularis act as leucine transport inhibitors

Six previously undescribed dihydro-β-agarofurans (bilocularins D-I) were isolated from the roots of Maytenus bilocularis. Compounds were evaluated for their leucine uptake inhibition in the human prostate cancer cell line, LNCaP.346