Anti-inflammatory meroterpenoids from the mangrove endophytic fungus Talaromyces amestolkiae YX1

Four previously undescribed meroterpenoids, amestolkolides A−D, were isolated from the mangrove endophytic fungus Talaromyces amestolkiae YX1. Amestolkolide B showed strong anti-inflammatory activity with IC50 value of 1.6 ± 0.1 μM.405