Nickel(II)-catalyzed addition reaction of arylboronic acids to isatins

A Ni-catalyzed addition of arylboronic acids to isatins was first developed. The reaction, driven by Ni(acac)2 and dppp, gave 3-aryl-3-hydroxy-2-oxindoles in up to 97% yield. Substituted phenylboronic acids along with fused-ring and heterocyclic boronic acids reacted with isatins smoothly.147