کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7845145 1508427 2014 27 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and surface functionalization of silica nanoparticles for nanomedicine
ترجمه فارسی عنوان
سنتز و عملکرد سطح نانوذرات سیلیکا برای نانومواد
کلمات کلیدی
سیلیکا، نانوذرات، تصویربرداری بیومدیکال، توزیع بیولوژیک، سم شناسی، تکنولوژی لغوی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
چکیده انگلیسی
There are a wide variety of silica nanoformulations being investigated for biomedical applications. Silica nanoparticles can be produced using a wide variety of synthetic techniques with precise control over their physical and chemical characteristics. Inorganic nanoformulations are often criticized or neglected for their poor tolerance; however, extensive studies into silica nanoparticle biodistributions and toxicology have shown that silica nanoparticles may be well tolerated, and in some case are excreted or are biodegradable. Robust synthetic techniques have allowed silica nanoparticles to be developed for applications such as biomedical imaging contrast agents, ablative therapy sensitizers, and drug delivery vehicles. This review explores the synthetic techniques used to create and modify an assortment of silica nanoformulations, as well as several of the diagnostic and therapeutic applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surface Science Reports - Volume 69, Issues 2–3, September–October 2014, Pages 132-158
نویسندگان
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