Synthesis of highly dispersed titanium dioxide nanoclusters on reduced graphene oxide for increased glucose sensing

Highly dispersed titanium dioxide nanocluster (TDN) was synthesized on reduced graphene oxide (RGO) in a toluene-water system under microwave irradiation. The prepared RGO-TDN hybrids were used to modify glassy carbon electrode for loading glucose oxidase. The fabricated glucose biosensor exhibits excellent performance for glucose sensing including low work potential (−0.7 V), high sensitivity (35.8 μA mM−1 cm−2), low detection limit (4.8 μM), wide linear range from 0.032 to 1.67 mM, small Michaelis-Menten constant (Km) (0.81 mM), and short response time (10 s).