کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7868984 | 1509164 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Osteoblast response to zirconia surfaces with different topographies
ترجمه فارسی عنوان
پاسخ استئوبلاست به سطوح زیرکونیا با توپوگرافی های مختلف
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کلمات کلیدی
فرهنگ سلولی، زیرکونیا، استئوبلاست، توپوگرافی، زیست سازگاری،
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
چکیده انگلیسی
Zirconia-3 mol% yttria ceramics were prepared with as-sintered, abraded, polished, and porous surfaces in order to explore the attachment, proliferation and differentiation of osteoblast-like cells. After modification, all surfaces were heated to 600 °C to extinguish traces of organic contamination. All surfaces supported cell attachment, proliferation and differentiation but the surfaces with grain boundary grooves or abraded grooves provided conditions for enhanced initial cell attachment. Nevertheless, overall cell proliferation and total DNA were highest on the polished surface. Zirconia sintered at a lower temperature (1300 °C vs. 1450 °C) had open porosity and presented reduced proliferation as assessed by alamarBlue⢠assay, possibly because the openness of the pores prevented cells developing a local microenvironment. All cells retained the typical polygonal morphology of osteoblast-like cells with variations attributable to the underlying surface notably alignment along the grooves of the abraded surface.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 57, 1 December 2015, Pages 363-370
Journal: Materials Science and Engineering: C - Volume 57, 1 December 2015, Pages 363-370
نویسندگان
H.M.T.U. Herath, L. Di Silvio, J.R.G. Evans,