کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7869498 | 1509166 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of gas produced by degradation of Mg-Zn-Zr Alloy on cancellous bone tissue
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
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چکیده انگلیسی
Mg-Zn-Zr alloy cylinders were implanted into the femoral condyles of Japanese big-ear white rabbits. X-ray showed that by 12Â weeks following implantation the implant became obscure, around which the low-density area appeared and enlarged. By 24Â weeks, the implant was more obscure and the density of the surrounding cancellous bone increased. Scanning electron microscopy examination showed bone tissue on the surface of the alloy attached by living fibers at 12Â weeks. Micro-CT confirmed that new bone tissue on the surface of the residual alloy implant increased from 12Â weeks to 24Â weeks. By 12Â weeks, many cavities in the cancellous bone tissue around the implant were noted with a CT value, similar to gas value, and increasing by 24Â weeks (PÂ <Â 0.01). Histological examination of hard tissue slices showed that bone tissue was visibly attached to the alloy in the femoral condyle at 12Â weeks. The trabecular bone tissues became more intact and dense, and the cavities were filled with soft tissue at 24Â weeks. In general, gas produced by the degradation of the Mg-Zn-Zr alloy can cause cavitation within cancellous bone, which does not affect osteogenesis of Mg alloy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 55, 1 October 2015, Pages 556-561
Journal: Materials Science and Engineering: C - Volume 55, 1 October 2015, Pages 556-561
نویسندگان
Jingbo Wang, Hongfeng Jiang, Yanze Bi, Jin e Sun, Minfang Chen, Debao Liu,