کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7869708 | 1509171 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Solution combustion synthesis of calcium phosphate particles for controlled release of bovine serum albumin
ترجمه فارسی عنوان
سنتز احتراق محلول ذرات فسفات کلسیم برای کنترل آزاد آلبومین سرم گاو
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
چکیده انگلیسی
Four different phase compositions of calcium phosphate (CaP) particles were prepared via a solution combustion method. X-ray diffraction (XRD) and Rietveld analysis results revealed that the variations in the nominal Ca/P (molar) ratios were found to provide a favorable control in the different proportions of CaP materials. Bovine serum albumin (BSA) was used as a model protein to study the loading and release behavior. The release profile indicated that the BSA release rates depended on the phase compositions of the CaP particles, and showed an order of TCP-BSAÂ >Â BCP-1-BSAÂ >Â BCP-2-BSAÂ >Â HA-BSA. The results suggested that the BSA protein release rate can be controlled by varying the phase compositions of CaP carriers. Moreover, the release process involved two stages: firstly surface diffusion via ion exchange and secondly intraparticle diffusion.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 50, 1 May 2015, Pages 194-200
Journal: Materials Science and Engineering: C - Volume 50, 1 May 2015, Pages 194-200
نویسندگان
Junfeng Zhao, Junjie Zhao, Yu Qian, Xiali Zhang, Feifei Zhou, Hong Zhang, Hongbin Lu, JianHua Chen, XuHong Wang, Wencong Yu,